Evaluation of response to I-131 ablative therapy in patients with differentiated thyroid carcinoma: A five year retrospective study [Persian]

Document Type: Original Article

Authors

Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Differentiated thyroid carcinomas usually show good uptake and response to I-131 ablative treatment. In this study, 90 patients following near total thyroidectomy who were referred to our institute for I-131 therapy are retrospectively studied. The patients are divided in two groups. Group 1 revealed complete ablation after one dose of I-131. Group 2 needed more than one dose of I-131 for ablation. 26 patients (28.9%) were Categorized in group 1 and 64 patients (71.1%) in group 2 patients. Comparison between the two groups revealed the highest success rate (Ablation with one dose of I-131) in male patients between 30-50 years of age, with mixed type of differentiated thyroid carcinoma without any evidence of local or distant metastasis.

Main Subjects