Tc-99m MIBI imaging in lymphomas: Comparison with T1-201 and Ga-67 scientigraphy

Document Type: Original Article

Authors

1 Department of Radiology, Hahnemann University Hospital, Philadelphia, PA, and Johns Hopkins Hospital, Baltimore, USA

2 Department of Radiation Oncology and Medical Oncology, Hahnemann University Hospital, Philadelphia, PA, and Johns Hopkins Hospital, Baltimore, USA

Abstract

Tc-99m MIBI has recently been used in the functional imaging of various tumors. This prospective study was performed to evaluate the role of Tc-99m MIBI imaging at the time of the initial staging, assessment of treatment response, follow-up studies and survaillance in Hodgkin’s and non-Hodgkin’s Iymphoma. 25 patients (14 with Hodgkin’s and 11 with non-Hodgkin’s Iymphoma) underwent 32 studies. The patient’s age range wa 19-73 years, with a mean age of 41.7 years. All patients underwent whole body planar imaging following intravenous injection of 20-25 mCi Tc-99m MIBI. Comparative imaging with 3 mCi Tl-201 and 10 mCi Ga-67 injection was done. Clinical, radiographic and biopsy correlation was obtained in all cases.

Main Subjects