Iranian Journal of Nuclear Medicine

Iranian Journal of Nuclear Medicine

[99mTc]Tc-MDP uptake in primary tumor of ovarian carcinoma following surgical removal of metastatic Sister Mary Joseph's node in umbilical herniorrhaphy

Document Type : Case Report

Authors
Amin Saber Tanha
Nasrin Raeisi
Haniye Elahifard
Somaye Barashki
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
10.22034/irjnm.2024.129804.1647
Abstract
We discussed a rare case of [99mTc]Tc-Methylene diphosphonate (MDP) uptake in the malignant ovarian tumor of a post-menopausal woman. She was referred for bone scintigraphy following the diagnosis of high-grade papillary serous adenocarcinoma of the ovary, which was identified after the detection of a Sister Mary Joseph's node during umbilical herniorrhaphy surgery. The whole body bone scan and post-void static images demonstrated a smeared area of persistent [99mTc]Tc -MDP uptake in the right pelvic region, adjacent to the bladder. Subsequent SPECT/CT imaging, prompted by lumbar pain, localized the uptake to the dystrophic calcification within the ovarian tumor. This case underscores the importance of paying attention to extra-osseous MDP uptake, such as within the ovary and uterine adnexa, as it can provide valuable diagnostic clues for further evaluation and increase the likelihood of identifying previously undetected pathologies.
Keywords
99mTc-MDP uptake
SPECT/CT
Extraosseous uptake
Metastatic ovarian carcinoma
Umbilical herniorrhaphy
Subjects
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