Research Institute for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran
Abstract
Thirty one patients with biologic and clinical diagnosis of hyperparathyroidism were submitted to thalium-technetium scan prior to exploration of the neck. Scan findings were compared with the pathologic results. Surgical exploration of the neck showed a parathyroid adenoma in 24 patients, parathyroid carcinoma in one patient, normal parathyroid in another patient and parathyroid hyperplasia in 5 patients. TTc scan correctly detected and localized 19 out of 24(79%) of adenomas, and 7 out of 20(35%) of parathyroid hyperplasia. The scan was negative in a normal case and correctly localized a parathyroid carcinoma. Five false negatives and 3 false positives were found in the adenoma group with specificity of 95.8%. Scan sensitivity did not change with adenoma size and weight or serum calcium, phosporous or PTH levels. In conclusion, TTS is a sensitive and useful procedure for preoperative localization of parathyroid adenomas.
Zakavi, S. R. and Saghari, M. (1995). Sensitivity and specificity of thallium-technetium subtraction scan in localization of the parathyroid adenoma [Persian]. Iranian Journal of Nuclear Medicine, 3(1), 2-7.
MLA
Zakavi, S. R. , and Saghari, M. . "Sensitivity and specificity of thallium-technetium subtraction scan in localization of the parathyroid adenoma [Persian]", Iranian Journal of Nuclear Medicine, 3, 1, 1995, 2-7.
HARVARD
Zakavi, S. R., Saghari, M. (1995). 'Sensitivity and specificity of thallium-technetium subtraction scan in localization of the parathyroid adenoma [Persian]', Iranian Journal of Nuclear Medicine, 3(1), pp. 2-7.
CHICAGO
S. R. Zakavi and M. Saghari, "Sensitivity and specificity of thallium-technetium subtraction scan in localization of the parathyroid adenoma [Persian]," Iranian Journal of Nuclear Medicine, 3 1 (1995): 2-7,
VANCOUVER
Zakavi, S. R., Saghari, M. Sensitivity and specificity of thallium-technetium subtraction scan in localization of the parathyroid adenoma [Persian]. Iranian Journal of Nuclear Medicine, 1995; 3(1): 2-7.
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