Document Type: Case Report
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Parotid metastasis originated from papillary thyroid carcinoma is extremely rare, especially as the first presentation of the disease. We present a 70-year-old man with a history of painless swelling in the right side of the neck. He was evaluated for parotid tumor and histopathologic examination revealed a poorly differentiated carcinoma in the parotid gland with suspicion of thyroid origin. The thyroid was examined and a small nodule was palpable in the right lobe of the thyroid that was found to be dedifferentiated papillary thyroid carcinoma upon total thyroidectomy. He received 5.5GBq of 131I and post-ablation whole body iodine scan showed thyroid remnant, cervical lymph node metastasis, lung and pericardial metastases and pleural effusion. He succumbed to his disease 8 months after diagnosis despite further treatments efforts including chemoradiation.