[99mTc]Tc-MDP uptake in primary tumor of ovarian carcinoma following surgical removal of metastatic Sister Mary Joseph's node in umbilical herniorrhaphy

Document Type : Case Report

Authors

Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

We discussed a rare case of [99mTc]Tc-Methylene diphosphonate (MDP) uptake in the malignant ovarian tumor of a post-menopausal woman. She was referred for bone scintigraphy following the diagnosis of high-grade papillary serous adenocarcinoma of the ovary, which was identified after the detection of a Sister Mary Joseph's node during umbilical herniorrhaphy surgery. The whole body bone scan and post-void static images demonstrated a smeared area of persistent [99mTc]Tc -MDP uptake in the right pelvic region, adjacent to the bladder. Subsequent SPECT/CT imaging, prompted by lumbar pain, localized the uptake to the dystrophic calcification within the ovarian tumor. This case underscores the importance of paying attention to extra-osseous MDP uptake, such as within the ovary and uterine adnexa, as it can provide valuable diagnostic clues for further evaluation and increase the likelihood of identifying previously undetected pathologies.

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References

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