Myocardial perfusion SPECT: Perfusion quantification

Document Type : Review Article

Author

Nuclear Medicine Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically.  Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be used routinely as complementary to visual analysis. Advantages of quantification are: greater confidence in interpretation, better reproducibility, diagnostic accuracy and measuring the degree of abnormality even subtle changes for serial comparisons. In this review, we look at the common features of such quantitative tools: 17-segment scoring system, polar maps including: raw, severity and extent polar maps, lung-to-heart ratio, transient ischemic dilation ratio, total perfusion deficit and spherecity index.

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References

Ficaro EP, Corbett JR. Advances in quantitative perfusion SPECT imaging. J Nucl Cardiol. 2004 Jan-Feb;11(1):62-70.
Watson DD. Quantitative SPECT techniques. Semin Nucl Med. 1999 Jul;29(3):192-203.
Berman DS, Hachamovitch R, Kiat H, Cohen I, Cabico JA, Wang FP, Friedman JD, Germano G, Van Train K, Diamond GA. Incremental value of prognostic testing in patients with known or suspected ischemic heart disease: a basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol. 1995 Sep;26(3):639-47.
Dabbagh Kakhki VR. Gated myocardial perfusion SPECT in patients with kidney transplantation: Semi-quantification. Iran J Nulc Med. 2013;21(2)44-45.
Dabbagh Kakhki VR, Zakavi SR, Sadeghi R, Emadzadeh MR, Vejdani A. Normal values of left ventricular functional indices in gated 99mTc-MIBI myocardial perfusion SPECT. Iran J Nucl Med. 2008;16(1),14-19.
Slomka P, Xu Y, Berman D, Germano G. Quantitative analysis of perfusion studies: strengths and pitfalls. J Nucl Cardiol. 2012 Apr;19(2):338-46.
Dabbagh Kakhki VR, Jabari H. Dipyridamole stress and rest gated 99mTc-sestamibi myocardial perfusion SPECT: left ventricular function indices and myocardial perfusion findings. Iran J Nucl Med. 2007;15(1):1-7. 
Russell PR, Wackers FJTH. Coronary artery disease detection: Exercise stress SPECT. In: Zaret BL, Beller GA. Clinical nuclear cardiology. 4th ed. Philadelphia: MOSBY; 2010. p. 600-630.
Germano G, Kavanagh PB, Slomka PJ, Van Kriekinge SD, Pollard G, Berman DS. Quantitation in gated perfusion SPECT imaging: the Cedars-Sinai approach. J Nucl Cardiol. 2007 Jul;14(4):433-54.
Lin GS, Hines HH, Grant G, Taylor K, Ryals C. Automated quantification of myocardial ischemia and wall motion defects by use of cardiac SPECT polar mapping and 4-dimensional surface rendering. J Nucl Med Technol. 2006 Mar;34(1):3-17.
Germano G, Slomka p, Berman DS. Computer aspects of myocardial imaging. In: Henkin RE et al. Nuclear Medicine. 2nd ed. Philadelphia: MOSBY; 2006. p. 600-630.
AutoQUANT® 7.0, Philips Medical Systems. URL: http://www.healthcare.philips.com/us_en/products/nuclearmedicine/support/index.wpd
Dabbagh Kakhki VR. Different aspects of transient ischemic dilation. Iran J Nucl Med. 2007;15(2):30-33.
Kakhki VR, Sadeghi R, Zakavi SR. Assessment of transient left ventricular dilation ratio via 2-day dipyridamole Tc-99m sestamibi nongated myocardial perfusion imaging. J Nucl Cardiol. 2007 Jul;14(4):529-36.
Abidov A, Germano G, Berman DS. Transient ischemic dilation ratio: a universal high-risk diagnostic marker in myocardial perfusion imaging. J Nucl Cardiol. 2007 Jul;14(4):497-500.
Iranian Journal of Nuclear Medicine
Volume 23, Issue 1 - Serial Number 43
Serial number: 43
January 2015
Pages 49-52

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