A 36-year-old woman with right upper quadrant abdominal pain since three months previously and no other significant medical history was referred for evaluation of an abdominal mass. Upon clinical examination, a large palpable mass in the mid -upper abdominal area was noted. Abdominal ultrasound and spiral CT-scan showed a large hepatic mass in the left liver lobe. The patient was referred for Tc-99m labeled RBC scintigraphy to assess the possibility of presence of liver hemangioma. The radionuclide imaging confirmed the diagnosis of hemangioma which in this case, the huge size of the lesion was of interest.